Grape seed extract was shown to against prostate cancer. Same group from UC also found that grape seed extract possessed in vivo anticancer efficacy against hormone-refractory human prostate cancer, which was
associated with grape seed extract 's antiproliferative, proapoptotic and antiangiogenic activities together with up regulation of insulin-like growth factor binding protein. They also found that grape seed extract could induce apoptotic death of human prostate carcinoma DU145 cells via mitochondrial
damage and cytochrome c release in cytosol resulting in PARP cleavage.
Source here.
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